You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air

https://titusjhjn216.halcyonledger.com/posts/the-link-between-crawl-space-rodents-and-the-air-inside-your-home

You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air and raise the risk of exposure to rodent-borne diseases.